Publications

AUTHORED BOOK:

Deary, I. J., Whalley, L. J., & Starr, J. M. (2009). A lifetime of intelligence: follow-up studies of the Scottish Mental Surveys of 1932 and 1947. Washington, DC: American Psychological Association.

2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

 

 

REFEREED JOURNAL ARTICLES:

 

In Press:

 

Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience.

Adams, H. H. et al.  (in press). LBC1936

 

APOE e4 status and poor glycaemic control predict white matter hyperintensity growth from 73-76 years. Neurobiology of Aging.

Cox SR, et al.  (in press). LBC1936

 

Cognitive abilities in later life and the onset of physical frailty: the Lothian Birth Cohort 1936. Journal of the American Geriatric Society.

Gale, C. R., et al. (in press). LBC1936

 

Life course activity participation from early, mid and later adulthood as determinants of cognitive ageing: The Lothian Birth Cohort 1921. Journal of Gerontology: Psychological Sciences.

Gow, A. J., et al. (in press). LBC1921.

 

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts. Translational Psychiatry.  

Hägg, S., et al. (in press). LBC1936

 

Development of a Short Form of the Attitudes to Ageing Questionnaire (AAQ) International Journal of Geriatric Psychiatry

Laidlaw, K., et al.  (in press) LBC1936

 

Improving data availability for brain image biobanking in helathy subjects: practice-based suggestions from an international multidisciplinary working group. Neuroimage,

Shenkin SD, et al. (in press). LBC1921 LBC1936

 

The application of retinal fundus camera imaging in dementia: a systematic review. Alzheimer’s and Dementia.

McGrory, S., et al.  (in press). LBC1936.

 

Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 study. British Journal of Ophthalmology.

McGrory, S., et al. (in press). LBC1936.

 

Childhood cognitive ability and incident dementia: follow up of participants in the 1932 Scottish Mental Survey into the tenth decade. European Journal of Epidemiology.

Russ, T. C., et al. (in press). LBC1921

 

 

E-published ahead of print.

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function. International Journal of Epidemiology.

Aschard, H., et al. (in press).  PMID: 28082375 LBC1936

 

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults. International Journal of Epidemiology.

Hagenaars, S. P., et al. (in press).  PMID: 26822939  .

 

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Molecular Psychiatry.

Trampush, J. W., et al. (in press). PMID: 28093568 LBC1936

 

Carotid disease at age 73 and cognitive change from age 70 to 76 years: A longitudinal cohort study. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism.

Wardlaw, J. M., et al. (in press).  PMID: 28155579 LBC1936

 

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics.

Wain, L. V., et al. (in press). PMID: 28166213 LBC1936

 

2017

 

The complex genetics of gait speed: genome-wide meta-analysis approach. Aging,

Ben-Avraham, D., et al. (2017).  PMID: 28077804  LBC1936

 

Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine. Pflugers Archiv: European Journal of Physiology,

Corre, T., et al. (2017). 10.1007/s00424-016-1913-7  LBC1936

 

Associations between hippocampal morphology, diffusion characteristics, and salivary cortisol in older men. Psychoneuroendocrinology,

Cox, S. R., et al. (2017). PMCID: PMC5078856  LBC1936

 

Novel genetic loci associated with hippocampal volume. Nature Communications

Hibar, D. P., et al. (2017).  PMCID: PMC5253632  LBC1936

 

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology

Ligthart, S., et al. (2017).  PMCID: PMC5151130  LBC1936

 

Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort. Neurology.

Luciano, M., et al. (2017).  PMCID: PMC5278943  LBC1936

 

Rare and low-frequency coding variants alter human adult height. Nature.

Marouli, E., et al. (2017).  PMCID: PMC5302847  LBC1921 LBC1936

 

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. PLoS Medicine.

Mendelson, M. M., et al. (2017).  PMCID: PMC5240936   LBC1921 LBC1936

 

Markers of Psychological Differences and Social and Health Inequalities: Possible Genetic and Phenotypic Overlaps. Journal of Personality.

Mõttus, R., et al. (in press). PMID: 26292196 LBC1936.

 

Impact of small vessel disease in the brain on gait and balance. Scientific Reports

Pinter, D., et al. (2017).  PMCID: PMC5278543  LBC1936.

 

Do Cognitive and Physical Functions Age in Concert from Age 70 to 76? Evidence from the Lothian Birth Cohort 1936. The Spanish Journal of Psychology

Ritchie, S. J., et al. (2017).  PMID: 27917739  LBC1936.

 

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Proceedings of the National Academy of Sciences of the United States of America

Schumann, G., et al. (2017).   PMCID: PMC5167198  LBC1936.

 

Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936. Neurobiology of Aging

Valdés Hernández, M. D. C., et al. (2017).  PMID: 28104542  LBC1936.

 

2016

The Movement of Research from the Laboratory to the Living Room: a Case Study of Public Engagement with Cognitive Science. Neuroethics

Broer, T., et al. (2016).  doi:10.1007/s12152-016-9259-6  LBC1936

 

DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging.

Chen, B., et al. (2016). PMID: 27690265  LBC1921 & LBC1936.

 

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population. Molecular Psychiatry.

Clarke, T.-K., et al. (2016). PMID: 25754080: LBC1921: LBC1936.

 

Bilingualism, social cognition and executive functions: a tale of chickens and eggs. Neuropsychologia.

Cox, S. R.,  et al. (2016). PMID: 27586077  LBC1936.

 

Associations between education and brain structure at age 73 years, adjusted for age 11 IQ. Neurology.

Cox, S. R.,  et al. (2016). PMCID: PMC5089529  LBC1936.

 

Volumetric and Correlational Implications of Brain Parcellation Method Selection: A 3-Way Comparison in the Frontal Lobes. Journal of Computer Assisted Tomography.

Cox, S. R., et al. (2016). PMCID: PMC4718185  LBC1936.

 

Getting Spearman off the Skyhook: One More in a Century (Since Thomson, 1916) of Attempts to Vanquish g. Psychological Inquiry

Deary, I. J., et al. (2016).  http://doi.org/10.1080/1047840X.2016.1186525 LBC1936

 

Processing speed differences between 70- and 83-year-olds matched on childhood IQ. Intelligence

Deary, I. J., & Ritchie, S. J. (2016). PMCID: PMC4796023  LBC1921 & LBC1936

 

Progression of White Matter Disease and Cortical Thinning Are Not Related in Older Community-Dwelling Subjects. Stroke; a Journal of Cerebral Circulation.

Dickie, D. A., et al. (2016). PMID: 26696646 LBC1936

 

Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936. Neurobiology of Aging

Dickie, D. A., et al. (2016).  PMCID: PMC4869590 LBC1936

 

Why is Mini-Mental state examination performance correlated with estimated premorbid cognitive ability? Psychological MedicineDykiert, D., et al. (2016).  

Dykiert, D., et al. (2016). PMID: 27377546 LBC1936

 

Intelligence and socioeconomic position in childhood in relation to frailty and cumulative allostatic load in later life: the Lothian Birth Cohort 1936. Journal of Epidemiology and Community Health

Gale, C. R., et al. (2016). PMCID: PMC4820036  Cohort:  LBC1936

 

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.

Hagenaars, S. P., et al. (2016).  PMID: 26809841 LBC1921 LBC1936.

 

Polygenic risk for ischaemic stroke is associated with cognitive ability. Neurology

Harris, S. E., et al. (2016). PMCID: PMC4762420 LBC1936.

 

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921. Mechanisms of Ageing and Development.

Harris, S. E., et al. (2016). PMID: 26876762 LBC1921 & LBC1936.

 

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions. Translational Psychiatry

Hill, W. D., et al. (2016). PMCID: PMC5290340    LBC1936

 

Examining non-syndromic autosomal recessive intellectual disability (NS-ARID) genes for an enriched association with intelligence differences. Intelligence.

Hill, W. D., et al.. (2016).  doi:10.1016/j.intell.2015.11.005   LBC1921 & LBC1936.

 

Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry

Howrigan, D. P., et al. PMID: 26390830 LBC1921 & 1936

 

GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular Psychiatry.

Ibrahim Verbaas, C. A., et al. (2016). PMCID: PMC4722802 LBC1921 & LBC1936.

 

Epigentic signatures of cigarette smoking. Circulation: Cardiovascular Genetics.

Joehanes, R., et al. (2016). PMID: 27651444 LBC1921, LBC1936.

 

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease. Nature Neuroscience.

Johnson, M. R., et al. (2016).  PMID: 26691832  LBC1936.

 

3D Shape Analysis of the Brain's Third Ventricle using a Midplane encoded Symmetric Template Model. Computer Methods and Programs in Biomedicine.

Kim, J, et al. (2016).  LBC1936.

 

Brain white matter structure and information processing speed in healthy older age. Brain Structure & Function

Kuznetsova, K. A., et al. (2016). PMCID: PMC4920858  LBC1936.

 

Trait conscientiousness and the personality meta-trait stability are associated with regional white matter microstructure. Social Cognitive and Affective Neuroscience

Lewis, G. J., et al. (2016). PMCID: PMC4967799  LBC1936

 

DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy. Aging

Lin, Q., et al. (2016). PMCID: PMC4789590  LBC1921, LBC1936.

 

Education-associated SNPs are enriched for brain function and disorders. Nature.

Okbay, A., et al. (2016). PMCID:  PMC4883595 LBC1921, LBC1936.

 

Life Course, Green Space and Health: Incorporating Place into Life Course Epidemiology. International Journal of Environmental Research and Public Health, 13.

Pearce, J., et al. (2016). PMCID: PMC4808994  LBC1936

 

Predictors of ageing-related decline across multiple cognitive functions. Intelligence

Ritchie, S, J., et al. (2016). PMCID: PMC5127886 LBC1936.

 

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behavior Genetics,

van den Berg, S. M., et al. (2016).  PMID: 26362575   LBC1921 & LBC1936

 

 

2015

Cognitive consequences of overweight and obesity in the ninth decade of life? Age and Ageing,

Aslan, A. K. D., et al. (2015). PMID: 25249169 LBC1921:

 

Association of allostatic load with brain structure and cognitive ability in later life. Neurobiology of Aging,

Booth, T., et al. (2015). PMCID: PMC4353502  LBC1936

 

Dietary factors and biomarkers of systemic inflammation in older people: the Lothian Birth Cohort 1936. The British Journal of Nutrition,

Corley, J., et al. (2015).  PMCID: PMC4579562   LBC1936

 

Serum cholesterol and cognitive functions: the Lothian Birth Cohort 1936. International Psychogeriatrics / IPA,

Corley, J., et al. (2015).  PMID: 25023928  LBC1936:

 

Compensation or inhibitory failure? Testing hypotheses of age-related right frontal lobe involvement in verbal memory ability using structural and diffusion MRI. Cortex

Cox, S. R., et al. (2015). PMCID: PMC4317301 :

 

Does white matter structure or hippocampal volume mediate associations between cortisol and cognitive ageing? Psychoneuroendocrinology,

Cox, S. R., et al. (2015).  PMID: 26298692 LBC1936.

 

Brain white matter integrity and cortisol in older men: the Lothian Birth Cohort 1936. Neurobiology of Aging,

Cox, S. R., et al. (2015). PMCID: PMC4274312  LBC1936.

 

Do personality traits moderate the manifestation of type 2 diabetes genetic risk? Journal of Psychosomatic Research,

Čukić, I., et al. (2015). PMCID: PMC4579920 LBC1936

 

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949). Molecular Psychiatry,

Davies, G., et al. (2015). PMCID: PMC4356746  LBC1921 & LBC1936.

 

Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Biological Psychiatry,

Debette, S., et al. Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. (2015).  PMID: 25648963 LBC1921 & LBC1936.

 

Brain iron deposits and lifespan cognitive ability. Age,

Del C Valdés Hernández, et al. (2015). PMID: 26378028 LBC1936

 

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry.

De Moor, M. H. M., et al. (2015).  PMCID: PMC4667957 LBC1921 & LBC1936.

 

Intelligence in childhood and atherosclerosis of the carotid and peripheral arteries in later life: the lothian birth cohort 1936. PLoS One.

Gale, C. R., et al. (2015). PMCID: PMC4411126 LBC1936.

 

Automated segmentation of multifocal basal ganglia T2*-weighted MRI hypointensities. NeuroImage, 105, 332–346.

Glatz, A., et al. (2015). PMCID: PMC4275576  LBC1936.

 

Genetic basis of a cognitive complexity metric.

Hansell, N. K., et al. (2015). PMCID: PMC4393228  LBC1936.

 

Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathologica Communications, 3, 53.

Henstridge, C. M., et al. (2015).  PMCID: PMC4559320 LBC1936

 

Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: the Lothian Birth Cohort 1936. The Journal of Nutrition, Health & Aging,

Hernández, M. del C. V., et al. (2015). PMID: 25560818 LBC1936

 

Common genetic variants influence human subcortical brain structures. Nature,

Hibar, D. P., et al. (2015). PMID: 25607358 LBC1936.

 

Modulation of genetic associations with serum urate levels by body-mass-index in humans. PloS One,

Huffman, J. E., et al. (2015). PMCID: PMC4374966  LBC1936

 

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood,

Huffman, J. E., et al. (2015).  PMID: 26105150 LBC1921 & LBC1936

 

Directional dominance on stature and cognition in diverse human populations. Nature,

Joshi, P. K., et al. (2015).  PMCID: PMC4516141  LBC1921 & LBC1936

 

Cigarette smoking and thinning of the brain’s cortex. Molecular Psychiatry

Karama, S., et al.  (2015). PMID: 25666755 LBC1936

 

Hippocampal Shape Modeling Based on a Progressive Template Surface Deformation and its Verification. IEEE Transactions on Medical Imaging,

Kim, J., et al. (2015).  PMID: 25532173 LBC1936

 

Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage,

Kochunov, P., et al. (2015).  PMCID: PMC4387079  LBC1936

 

Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Strok,

Lopez, L. M., et al. (2015). PMCID: PMC4306534  LBC1936.

 

Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities. Twin Research and Human Genetics:

Luciano, M., et al. (2015). PMCID: PMC4747328  LBC1936

 

APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds. International Journal of Stroke.

Lyall, D. M., et al.  (2015). PMID: 26310205 LBC1936

 

White matter hyperintensities and normal-appearing white matter integrity in the aging brain. Neurobiology of Aging,

Maniega, S. M., et al. (2015).  PMCID: PMC4321830  LBC1936.

 

DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology,

Marioni, R. E., et al. (2015). PMCID: PMC4350614  LBC1936.

 

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology.

Marioni, R. E., et al. (2015).  PMID: 25617346 Cohort: LBC1936

 

Childhood cognitive ability moderates later-life manifestation of type 2 diabetes genetic risk. Health Psycholog.

Mõttus, R., et al. (2015). PMID: 25603418 Cohort: LBC1936

 

Disentangling wording and substantive factors in the Spiritual Well-Being Scale. Psychology of Religion and Spirituality,

Murray, A. L., et al.  (2015). http://doi.org/10.1037/a0038001   Cohort: LBC1921

 

Proton spectroscopic imaging of brain metabolites in basal ganglia of healthy older adults. Magnetic Resonance Materials in Physics, Biology, and Medicine. Magma (New York, N.Y.).

Parikh, J., et al.  (2015). PMID: 25312604  Cohort: LBC1936

 

Coupled changes in brain white matter microstructure and fluid intelligence in later life. The Journal of Neuroscience.

Ritchie, S. J., et al. (2015). PMCID: PMC4452562 LBC1936

 

Is education associated with improvements in general cognitive ability, or in specific skills? Developmental Psychology.

Ritchie, S. J., et al . (2015). PMCID: PMC4445388 LBC1936

 

Brain volumetric changes and cognitive ageing during the eighth decade of life. Human Brain Mapping.

Ritchie, S. J., et al. (2015).  PMID: 26769551 Cohort: LBC1936

 

Beyond a bigger brain: Multivariable structural brain imaging and intelligence. Intelligence.

Ritchie, S. J., et al. (2015).  PMCID: PMC4518535 LBC1936

 

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. American Journal of Human Genetics,

Shah, S., et al. (2015).  PMCID: PMC4572498 LBC1921 & LBC1936

 

Total MRI load of cerebral small vessel disease and cognitive ability in older people. Neurobiology of Aging, 36, 2806–2811.

Staals, J., et al. (2015). PMID: 26189091 LBC1936

 

Retinal Vascular Fractal Dimension, Childhood IQ, and Cognitive Ability in Old Age: The Lothian Birth Cohort Study 1936. PloS One,

Taylor, A. M., et al. (2015). PMCID: PMC4376388 LBC1936

 

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment. Neuropsychiatric Genetics, 168, 363–373.

Trampush, J. W., et al, (2015). PMID: 25951819 LBC1936

 

Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: the Lothian Birth Cohort 1936. The Journal of Nutrition, Health & Aging,

Hernández, M. del C. V., et al. (2015). PMID: 25560818 LBC1936

 

A comparison of location of acute symptomatic vs. ‘silent’ small vessel lesions. International Journal of Stroke.

Valdes Hernandez, et al. (2015). PMID: 26120782  LBC1936

 

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular Genetics.

Verhaaren, B. F. J., et al.  (2015). PMID: 25663218 Cohort: LBC1936

 

Development and initial evaluation of a semi-automatic approach to assess perivascular spaces on conventional magnetic resonance images. Journal of Neuroscience Methods.

Wang, X., et al.   (2015).  PMID: 26416614  LBC1936

 

 

2014

 

Blood Pressure, Internal Carotid Atery Flow Parameters and Age-Related White Matter Hyperintensities. Hypertension.

Aribisala, B. S., et al. (2014).  PMCID: PMC3984108 LBC1936

 

Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing. Age and Ageing.

Aribisala, B. S. et al. (2014). (PMID: 24936580) LBC1936

 

Circulating inflammatory markers are associated with magnetic resonance imaging-visible perivascular spaces but not directly with white matter hyperintensities. Stroke.

Aribisala, B. S., et al. (2014).   PMID: 24399375  LBC1936

 

Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.  Molecular Psychiatry.

Benyamin, B. et al. (2014).   PMID: 23358156  LBC1921 & LBC1936.

 

Personality, Health, and Brain Integrity: The Lothian Birth Cohort Study 1936. Health Psychology.

Booth, T., et al. (2014). PMID: 24245834. LBC1936.

 

Physical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts.  Age

Cooper, R.,at al. (2014).  PMID:23818103  LBC1921.

 

A systematic review of brain frontal lobe parcellation techniques in magnetic resonance imaging.  Brain Structure & Function,

Cox, S. R., et al. (2014). PMID: 23474540  LBC1936

 

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. Molecular Psychiatry

Davies, G., et al. (2014). PMID: 23207651 LBC1921 & LBC1936,

 

Differentiation of calcified regions and iron deposits in the ageing brain on conventional structural MR images.  Journal of Magnetic Resonance Imaging,

Del C. Valdés Hernández, M., et al. (2014). doi:10.1002/jmri.24348  LBC1936

 

Gender and telomere length: Systematic review and meta-analysis. Experimental Gerontology.

Gardner, M., Halcyon study team, et al (2014).   PMID: 24365661  LBC1921

 

Polygenic Risk for Alzheimer’s Disease is not Associated with Cognitive Ability or Cognitive Aging in Non-Demented Older People.  Journal of Alzheimer’s Disease

Harris, S. E., et al. ( 2014).   PMID: 24246418  LBC1936

 

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins. Translational Psychiatry,

Hill, W. D., et al. (2014).  PMCID: PMC3905224  LBC1921 & LBC1936.

 

Functional Gene Group Analysis Indicates No Role for Heterotrimeric G Proteins in Cognitive Ability.  PLoS ONE

Hill, W. D., et al. (2014).  PMID: 24626473   LBC1921 & LBC1936.

 

Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age. Molecular psychiatry.

Karama, S., et al. (2014). PMID: 23732878 LBC1936.

 

Lower ankle-brachial index is related  to worse cognitive performance in old age.  Neuropsychology.

Laukka, E. et al. (2014).  PMCID: PMC3942013  LBC1921 & LBC1936.

 

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consortium (COGENT). Molecular Psychiatry,

Lencz, T., et al. (2014). PMID: 24342994  LBC1936

 

Predicting cognitive ability in ageing cohorts using Type 2 diabetes genetic risk. Diabetic Medicine

Luciano, M., et al. (2014).  PMID: 24344862 LBC1921 & LBC1936.

 

The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability. Proceedings. Biological Sciences / The Royal Society,

Marioni, R. E., et al. (2014).  PMID: 24573858 LBC1921 & LBC1936.

 

Towards understanding the links between health literacy and physical health. Health Psychology.

Mõttus, R., et al. (2014) PMID: 23437854 LBC1936

 

School reform and opportunity throughout the lifecourse: the Lothian Birth Cohort 1936. School Effectiveness and School Improvement.

Paterson, L., et al. (2014). doi:10.1080/09243453.2013.772903. LBC1936.

 

Alcohol consumption and lifetime change in cognitive ability: a gene × environment interaction study. Age.

Ritchie, S. J., et al. (2014). PMID: 24652602  LBC1936

 

Life course influences of physical and cognitive function and personality on attitudes to aging in the Lothian Birth Cohort 1936. International Psychogeriatrics / IPA,

Shenkin, S. D., et al (in press).  PMID: 24622392  LBC1936

 

Structure and correlates of cognitive aging in a narrow age cohort. Psychology and Aging.

Tucker-Drob, E. M., et al. (2014). PMID: 24955992 LBC1936

 

708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. Molecular psychiatry.

Thomson, P., et al. (2014) PMID: 23732877 LBC1936

 

Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities.  Neurology.

Wardlaw, J. M., et al. (2014).  PMID: 24623838  LBC1936

 

 

2013

 

Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme.  PloS one

Alfred, T., et al (2013).  PMID: 23894584   LBC1921

 

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions.  European journal of human genetics

Amin, N., et al. (2013). PMID: 23211697 LBC1921 & LBC1936.

 

Assessing the performance of atlas-based prefrontal brain parcellation in an aging cohort. Journal of computer assisted tomography

Aribisala, B. S., et al. (2013).  PMID: 23493216  LBC1936

 

Associations between level and change in physical function and brain volumes.  PloS One,

Aribisala, B. S., et al. (2013). PMID: 24265818    LBC1936

 

Quantitative multi-modal MRI of the Hippocampus and cognitive ability in community-dwelling older subjects.  Cortex

Aribisala, B. S., et al. (2013).  PMID: 24561387  LBC1936

 

Brain atrophy associations with white matter lesions in the ageing brain: the Lothian Birth Cohort 1936.  European radiology.

Aribisala, B. S., et al. (2013). PMID: 23114884 LBC1936

 

Brain white matter tract integrity and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort, 1936.  Neuropsychology.

Booth, T., et al. (2013). PMID: 23937481. LBC1936.

 

Thyroid stimulating hormone, free thyroxine and cognitive ability in old age: the Lothian Birth Cohort 1936. Psychoneuroendocrinology.

Booth, T., et al. (2013)  PMID: 22959930 LBC1936

 

Modeling multisystem biological risk in later life: allostatic load in the Lothian birth cohort study 1936.  American journal of human biology

Booth, T., et al. (2013). PMID: 23754497  LBC1936.

 

Do dietary patterns influence cognitive function in old age? International psychogeriatrics.  

Corley, J., et al. (2013). PMID: 23732046 LBC1936

 

An intelligent Scotland: Professor Sir Godfrey Thomson and the Scottish Mental Surveys of 1932 and 1947. Journal of the British Academy

Deary, I. J., (2013).  doi:10.5871/jba/001.095  LBC1921 & LBC1936.

 

The stability of intelligence from age 11 to age 90 years: the Lothian Birth Cohort 1921.  Psychological Science.

Deary, I. J., et al. (2013). PMID: 24084038  LBC1921.

 

Retrospective validation of WTAR and NART scores as estimators of prior cognitive ability using the Lothian Birth Cohort 1936.  Psychological Assessment.

Dykiert, D., et al. (2013). (PMID: 23815111). Cohort: LBC1936.

 

Telomere length and physical performance at older ages: an individual participant meta-analysis.  PLoS One.

Gardner, M. P., et al. (2013). (PMID: 23922731). LBC1921.

 

Characterization of multifocal T2*-weighted MRI hypointensities in the basal ganglia of elderly, community-dwelling subjects.  NeuroImage,

Glatz, A., et al. (2013). PMID: 23769704). LBC1936.

 

Cytomegalovirus infection and cognitive abilities in old age.  Neurobiology of Ageing.

Gow, A. J., et al. (2013). PMID: 23434472 LBC1936.

 

Which social network or support factors are associated with cognitive abilities in old age?

Gerontology,

Gow, A. J., et al. (2013). (PMID: 23711796). LBC1936.:

 

Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme.  PloS one.

Hardy, R., et al. (2013) PMID: 23437142 Cohort: LBC1921

 

Towards the automatic computational assessment of enlarged perivascular spaces on brain magnetic resonance images: A systematic review.  JMRI.

Hernández, M. del C. V., et al. (2013). PMID: 23441036. LBC1936

 

Symmetry of the face in old age reflects childhood social status.  Economics & Human Biology.

Hope, D., et al. (2013).  PMID: 21820367, LBC1921

 

Bodily symmetry increases across human childhood.  Early human development

Hope, D., et al. (2013).  PMID: 23375947  LBC1921

 

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA-DTI working group.  NeuroImage,

Jahanshad, N., et al. (2013). PMID: 23629049 LBC1936.

 

Seropositivity for CMV and IL-6 levels are associated with grip strength and muscle size in the elderly.  Immunity & ageing

Kilgour, A. H., et al. (2013). PMID: 23938060  LBC1936

 

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.  Nature genetics,

Köttgen, A., et al. (2013).   PMID: 23263486 LBC1936

 

Retinal nerve fibre layer thickness and cognitive ability in older people: the Lothian Birth Cohort 1936 study.  BMC Ophthalmology.

Laude, A., et al. (2013). (PMID: 23822668). LBC1936

 

ADRB2, brain white matter integrity and cognitive ageing in the Lothian Birth Cohort 1936. Behavior genetics

Lyall, D. M., et al. (2013). PMID: 23229623 LBC1936

 

Alzheimer’s disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.  PloS One

Lyall, D. M., et al. (2013).  PMID: 24260406  LBC1936

 

Neuroticism, depressive symptoms and white-matter integrity in the Lothian Birth Cohort 1936.  Psychological medicine

McIntosh, A. M., et al. (2013).  PMID: 22785087  LBC1936

 

Polygenic Risk for Schizophrenia Is Associated with Cognitive Change Between Childhood and Old Age. Biological psychiatry.

McIntosh, A. M., et al. (2013) PMID: 23419543 LBC1921 & LBC1936.

 

Diabetes and life-long cognitive ability.  Journal of Psychosomatic Research.

Mottus, R., et al. (2013). ( PMID: 23972418). LBC1936

 

Personality traits and inflammation in individuals aged around 70 and 73 years.  Psychosomatic Medicine.
Mõttus, R., et al. (2013). PMID: 23197841. LBC1936.

 

The associations between personality, diet and body mass index in older people.  Health Psychology.

Mõttus, R., et al. (2013). PMID: 21928903 LBC1936

 

Predicting tooth loss in older age: interplay between personality and socioeconomic status.  Health Psychology.

Mõttus, R., et al. (2013). PMID: 22329425 LBC1936

 

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genetics, 9, e1003796.

O’Seaghdha, C. M, et al. (2013). LBC1936

 

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function.  Plos Genetics

Porcu, E., et al. (2013). PMID: 23408906 LBC1921 & LBC1936.

 

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.  Science,

Rietveld, C. A., et al. (2013). PMID: 23722424 LBC1921 & LBC1936.

 

Education Is Associated With Higher Later Life IQ Scores, but Not With Faster Cognitive Processing Speed.  Psychology and aging.

Ritchie, S. J., et al. (2013). PMID: 23276218 LBC1936

 

Estimated maximal and current brain volume predict cognitive ability in old age.  Neurobiology of Aging.

Royle, N. A., et al. (2013). (PMID: 23850342). LBC1936

 

Influence of thickening of the inner skull table on intracranial volume measurement in older people. Magnetic Resonance Imaging.

Royle, N. A., et al. (2013). PMID: 23453763. LBC1936.

 

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.  Circulation

Sabater-Lleal, M., et al. (2013).  PMID: 23969696  LBC1921 & LBC1936.

 

Incidental findings on brain MR imaging in older community-dwelling subjects are common but serious medical conditions are rare.  PloS One.

Sandeman, E. M., et al. (2013). (PMID: 23967214). LBC1936

 

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.  PLoS genetics

Thun, G. A., et al. (2013).  PMCID: PMC3749935  LBC1936

 

Brain white matter damage in aging and cognitive ability in youth and older age.  Neurobiology of aging,

Hernandez, M.D.C.V, et al. (2013). (PMCID: PMC3898072). LBC1936

 

Intellect and cognitive performance in the Lothian Birth Cohort 1936. Psychology and aging,

Von Stumm, S., et al. (2013). PMID: 24041000  LBC1936

 

 

2012

 

Psychosocial factors and health as determinants of quality of life in community-dwelling older adults. Quality of Life Research.

Brett, C. E., et al. (2012).  PMID: 21706382, LBC1921 & LBC1936

 

Processing speed and visuospatial executive function predict visual working memory ability in older adults. Experimental Aging Research.

Brown, L. A., et al. (2012).  PMID: 22224947 LBC1936

 

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.  Human molecular genetics,

Cipriani, V., et al. (2012). PMID: 22694956  LBC1921

 

Smoking, childhood IQ, and cognitive function in old age. Journal of Psychosomatic Research, 73, 132-138.

Corley, J., et al. (2012).  PMID: 22789417 LBC1936

 

Meta-analysis of genome-wide personality association studies for personality. Molecular Psychiatry.

de Moor., et al. (2012) PMID: 21173776 LBC1936

 

Cohort profile: The Lothian Birth Cohorts of 1921 and 1936. International Journal of Epidemiology.

Deary, I. J., et al. (2012). PMID: 22253310, LBC1921 & LBC1936

 

Genetic contributions to stability and change in intelligence from childhood to old age.  Nature.

Deary, I. J., et al. (2012). PMID: 22258510 LBC1921 & LBC1936

 

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.  Nature Genetics.

Dunlop, M. G., et al. (2012) PMID: 22634755 LBC1921 & LBC1936

 

Predicting mortality from human faces.  Psychosomatic Medicine.

Dykiert, D., et al. (2012). PMID: 22753633, LBC1921

 

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.  American journal of human genetics,

Franceschini, N., et al. (2012). PMID: 23732046 LBC1936

 

Cognitive function in childhood and lifetime cognitive change in relation to mental wellbeing in four cohorts of older people. PLoS One.

Gale, C. R., et al. (2012)  PMID: 22970320 LBC1921

 

The Role of Variation at AβPP, PSEN1, PSEN2, and MAPT in Late Onset Alzheimer’s Disease. Journal of Alzheimer’s Disease.

Gerrish, A., et al. (2012). PMID: 22027014 LBC1921 & LBC1936

 

Neuroprotective lifestyles and the aging brain: activity, atrophy, and white matter integrity.  Neurology.

Gow, A. (2012). PMID: 23091073 LBC1936

 

Reverse causation in activity-cognitive ability associations: The Lothian Birth Cohort 1936.  Psychology and Aging.

Gow, A. J., et al.  (2012). PMID: 21644808, LBC1936

 

Is age kinder to the initially more able?: yes and no. Intelligence.

Gow, A. J., et al. (2012). doi:10.1016/j.intell.2011.10.007, LBC1921

 

The Association Between Retinal Vessel Morphology and Retinal Nerve Fiber Layer Thickness in an Elderly Population. Ophthalmic Surgery, Lasers & Imaging.

Grinton, M. E., et al. (2012). PMID: 22882008, LBC1936

 

Pathways from childhood intelligence and socio-economic status to late-life cardiovascular disease risk. Health Psychology.

Hagger-Johnson, G., et al. (2012). PMID: 22309883, LBC1936

 

The role of ECE1 variants in cognitive ability in old age and Alzheimer’s disease risk. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics

Hamilton, G., et al. (2012).   PMID: 22693153 LBC1936

 

Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936.  Neurobiology of Aging.

Harris, S. E., et al. (2012). PMID: 21194798, LBC1936

 

Color fusion of magnetic resonance images improves intracranial volume measurement in studies of aging.  Open Journal of Radiology.

Hernandez, M. D.C.V, et al. (2012) (doi:10.4236/ojrad.2012.21001)  LBC1936

 

Minor physical anomalies, intelligence, and cognitive decline. Experimental Aging Research.

Hope, D., et al. (2012).  PMID: 22540382 LBC1921

 

Can we spot deleterious ageing in two waves of data? The Lothian Birth Cohort 1936 from ages 70 to 73.  Longitudinal and Life Course Studies.

Johnson, W., et al. (2012) (http://www.llcsjournal.org/index.php/llcs/article/view/198  LBC1936

 

Design and validation of a novel method to measure cross-sectional area of neck muscles included during routine MR brain volume imaging.  PLoS One.

Kilgour, A. H. M. (2012). (PMID: 22509305) LBC1936

 

No evidence for sexual dimorphism of facial width-to-height ratio in four large adult samples.  Evolution and Human Behavior.

Lefevre, C. E., et al. (2012)  doi:10.1016/j.evolhumbehav.2012.03.002 LBC1921

 

A genome-wide search for genetic influences and biological pathways related to the brain's white matter integrity.  Neurobiology of Aging.

Lopez, L. M., et al. (2012). PMID: 22425255 LBC1936

 

Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts. European Journal of Human Genetics: EJH.

Lopez, L. M., et al. (2012). PMID: 22045296, LBC1921 & LBC1936

 

Longevity candidate genes and their association with personality traits in the elderly. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics.

Luciano, M., et al. (2012). PMID: 22213687 LBC1921 & LBC1936

 

Effects of gene copy number variants on personality and mood in ageing cohorts. Personality and Individual Differences.

Luciano, M., et al. (2012). doi:10.1016/j.paid.2011.12.019  LBC1921 & LBC1936

 

Depressive symptoms and diet: Their effects on prospective inflammation levels in the elderly. Brain, Behavior, and Immunity.

Luciano, M., et al. (2012). PMID: 22056839 LBC1936

 

Genome-wide association uncovers shared genetic effects among personality traits and mood states. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B, 684–695.

Luciano, M., et al. (2012). PMID: 22628180 LBC1921 & LBC1936

 

Genetic copy number variation and general cognitive ability. PLoS One.

MacLeod, A. K., et al. (2012)  PMID: 23300510  LBC1921 & LBC1936

 

Evidence of inbreeding depression on human height. PLoS genetics.

McQuillan, R., et al. (2012).  PMID: 22829771  LBC1921 & LBC1936

 

‘On the street where you live’: Neighbourhood deprivation and quality of life among community-dwelling older people in Edinburgh, Scotland.  Social science & medicine,

Mõttus, R., et al. (2012).  PMID: 22401647  LBC1936

 

Personality traits in old age: Measurement and rank-order stability and some mean-level change. Psychology and Aging.

Mõttus, R., et al. (2012). PMID: 21604884 LBC1921 & LBC1936

 

Correlates of personality trait levels and their changes in very old age: The Lothian Birth Cohort 1921. Journal of Research in Personality.

Mõttus, R., et al. (2012). doi:10.1016/j.jrp.2012.02.004 LBC1921

 

Does cognitive ability predict mortality in the ninth decade?: the Lothian Birth Cohort 1921.  Intelligence.

Murray, C., et al. (2012)  doi:10.1016/j.intell.2012.05.003 LBC1921

 

Brain white matter tract integrity as a neural foundation for general intelligence. Molecular psychiatry.

Penke, L., et al. (2012). PMID: 22614288, LBC1936

 

Brain iron deposits are associated with general cognitive ability and cognitive aging.  Neurobiology of Aging.

Penke, L., et al. (2012). PMID: 20542597 LBC1936

 

APOE E4 status predicts age-related cognitive decline in the ninth decade: longitudinal follow-up of the Lothian Birth Cohort 1921. Molecular Psychiatry.

Schiepers, O. J. G., et al. (in press). PMID: 21263443 LBC1921

 

Identification of common variants associated with human hippocampal and intracranial volumes. Nature genetics.

Stein, J. L., et al. (2012) PMID: 22504417 LBC1936

 

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genetics.

Stolk, L., et al. (2012). PMID: 22267201 LBC1936

 

Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease. American Journal of Human Genetics.

Tang, W., et al. (2012). PMID: 22703881  LBC1921 & LBC1936

 

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.  Lancet neurology.

Traylor, M. (2012). PMID: 23041239 LBC1936

 

Automatic segmentation of brain white matter and white matter lesions in normal aging: comparison of five multispectral techniques.  Magnetic Resonance Imaging.

Valdés Hernández, M. D. C. (2012).  PMID: 22071410 LBC1936

 

Seventy-five genetic loci influencing the human red blood cell.  Nature.

van der Harst, P. (2012). PMID: 23222517 LBC1936

 

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Translational Psychiatry, 2, e102.

Vinkhuyzen, A. A. E., et al. (2012).  PMID: 22832902 LBC1921 and LBC1936

 

Typical intellectual engagement and cognition in the ninth decade of life: The Lothian Birth Cohort 1921. Psychology and Aging.

von Stumm, S., et al. (2012). PMID: 22182363 LBC1921

 

Do personality scale items function differently in people with high and low IQ? Psychological Assessment.

Waiyavutti, C., et al. (2012). PMID: 22082036 LBC1936       

 

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. American journal of respiratory and critical care medicine,

Wilk, J. B., et al. (2012). PMID: 22837378 LBC1936

 

Profiles of physical, emotional and psychological wellbeing in the Lothian Birth Cohort 1936. BMC Geriatrics.

Zammit, A. et al.(2012). (PMID: 23088370). LBC1936.

 

 

2011    

 

Absence of association of a SNP in the TERT-CLPTM1L locus with age-related phenotypes in a large multi-cohort study: the HALCyon program. Aging Cell.

Alfred, A., et al. (2011). PMID: 21332924 LBC1921

 

ACTN3 genotype, athletic status, and life course physical capability: meta-analysis of the published literature and findings from nine studies. Human Mutation.

Alfred, T., et al. (2011). PMID: 21542061 LBC1921

 

Skin ageing and oxidative stress in a narrow-age cohort of older adults. European Geriatric Medicine.

Allerhand, M., et al. (2011). doi:10.1016/j.eurger.2011.04.009 LBC1921

 

Genome-wide association and large-scale follow-up identifies 16 new loci influencing lung function. Nature Genetics.

Artigas, M. S., et al. (2011). PMID: 21946350  LBC1936

 

Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS One.

Birnie, K., et al. (2011). PMID: 21297868 Cohort: LBC1921

 

Flavonoid intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936. British Journal of Nutrition.

Butchart, C., et al. (2011). PMID: 21303571 LBC1936

 

Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies. PLoS One.

Cooper, R., et al. (2011). PMID: 22114723 LBC1921

 

Alcohol intake and cognitive abilities in old age: the Lothian Birth Cohort 1936 study.  Neuropsychology.

Corley, J., et al. (2011). PMID: 21381824 LBC1936

 

Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Molecular Psychiatry.

Davies, G., et al. (2011). PMID: 21826061 LBC1921 & LBC1936

 

Losing one's grip: a bivariate growth curve model of grip strength and non-verbal reasoning from age 79 to age 87 years in the Lothian Birth Cohort 1921. Journal of Gerontology: Psychological Sciences.

Deary, I. J., et al. (in press). PMID: 21743039  LBC1921

 

Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS One.

Frank, R. A. W., et al. (2011). PMID: 21559497 LBC1921

 

Factors associated with symptoms of anxiety and depression in five cohorts of community-based older people: the HALCyon programme. Psychological Medicine.

Gale, C. R., et al. (2011). PMID: 21349224 LBC1921

 

New gene functions in megakaryopoeisis and platelet formation. Nature.

Gieger, C., et al. (2011). PMID: 22139419 LBC1921 & LBC1936

 

Stability and change in intelligence from age 11 to ages 70, 79 and 87: The Lothian Birth Cohorts of 1921 and 1936. Psychology and Aging.

Gow, A. J., et al. (2011). PMID: 20973608 LBC1921 & LBC1936

 

A stairway to heaven?: Structure of the Religious Involvement and Spiritual Well-Being Scale. Journal of Religion and Health.

Gow, A. J., et al. (2011). PMID: 20614185 LBC1921

 

Alzheimer's disease genes are associated with measures of cognitive ageing in the Lothian Birth Cohorts of 1921 and 1936. International Journal of Alzheimer's Disease.

Hamilton, G., et al. (2011). PMID: 21766012 LBC1921 & LBC1936

 

Vision and intelligence at age 83 in the Lothian Birth Cohort 1921. Intelligence.

Henderson, R. D., et al. (2011). doi:10.1016/j.intell.2011.02.005  LBC1921

 

Fluctuating asymmetry and personality. Personality and Individual Differences.

Hope, D., et al. (2011). doi:10.1016/j.paid.2010.08.020 LBC1921

 

Psychological and physical health at age 70 in the Lothian Birth Cohort 1936: links with early life IQ, SES, and current cognitive function and neighborhood environment. Health Psychology.

Johnson, W., et al. (2011). PMID: 21299289 LBC1936

 

Placing inspection time, reaction time, and perceptual speed in the broader context of cognitive ability: the VPR model in the Lothian Birth Cohort 1936. Intelligence.

Johnson, W., & Deary, I. J. (2011). doi:10.1016/j.intell.2011.07.003  LBC1936

 

A pilot study of urinary peptides as biomarkers for intelligence in old age. Intelligence.

Lopez, L. M., et al. (2011). doi:10.1016/j.intell.2010.11.001 LBC1936

 

Quantification of parapapillary atrophy and optic disc. Investigative Ophthalmology & Visual Science.

Lu, C.-K., et al. (2011). PMID: 21467185 LBC1936

 

Whole genome association scan for genetic polymorphisms influencing information processing speed. Biological Psychology.

Luciano, M., et al. (2011).  PMID: 21130836 LBC1921 & LBC1936

 

Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts. Behavior Genetics.

Marioni, R. E., et al. (2011). PMID: 19821022 LBC1936

 

Antioxidant and B vitamin intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936. European Journal of Clinical Nutrition.

McNeill, G., et al. (2011). PMID: 21346712 LBC1936

 

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome wide association data. Translational Psychiatry.

Middledorp, C. M., et al. (2011) (PMID: 22833196) LBC1936

 

How useful are the SF-36 subscales in older people? Mokken scaling of data from the HALCyon programme. Quality of Life Research.

Mishra, G. D., et al. (2011). PMID: 21225350 LBC1921

 

Which aspects of subjectively-reported quality of life are important in predicting mortality beyond known risk factors? The Lothian Birth Cohort 1921 study. Quality of Life Research.

Murray, C., et al. (2011). PMID: 20661775 LBC1921

 

The association between cognitive ability across the lifespan and health literacy in old age: the Lothian Birth Cohort 1936. Intelligence.

Murray, C., et al. (2011). doi:10.1016/j.intell.2011.04.001 LBC1936

 

The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects. American Journal of Human Genetics: Neuropsychiatric Genetics.

Rizzi, T. S., et al. (2011). PMID: 21302343 LBC1936

 

MTHFR polymorphisms and cognitive ageing in the ninth decade: the Lothian Birth Cohort 1921. Genes, Brain and Behavior.

Schiepers, O., et al. (2011). PMID: 21255267 LBC1921

 

Genetic predictors of fibrin D-Dimer levels in healthy adults. Circulation.

Smith, N. L., et al. (2011). PMID: 21502573 LBC1921 & LBC1936

 

Socio-economic position predicts grip strength and its decline between 79 and 87 years: the Lothian Birth Cohort 1921. Age and Ageing.

Starr, J. M., & Deary, I. J. (2011).  PMID: 21705769 LBC1921

 

Blood pressure, socio-economic status and health in the Lothian 1921 Birth Cohort: a longitudinal study. Public Health.

Starr, J. M., & Deary, I. J. (2011). PMID: 21420696 LBC1921

 

Sex differences in blood cell counts in the Lothian Birth Cohort 1921 between 79 and 87 years. Maturitas.

Starr, J. M., & Deary, I. J. (2011).  PMID: 21641736 LBC1921

 

Reliability of two techniques for assessing cerebral iron deposits with structural magnetic resonance imaging. Journal of Magnetic Resonance Imaging: JMRI.

Valdés Hernández, M. C., et al. (2011).  PMID: 21182121 LBC1936

 

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics.

Wain, L.V., et al. (2011). PMID: 21909110 LBC1921 & LBC1936

 

Brain ageing, cognition in youth and old age, and vascular disease in the Lothian Birth Cohort 1936: rationale, design and methodology of the imaging protocol. International Journal of Stroke.

Wardlaw, J. M., et al. (2011). PMID: 22111801 Cohort: LBC1936

 

2010

 

Is body mass index in old age related to cognitive abilities? The Lothian Birth Cohort 1936 study. Psychology and Aging.

Corley, J., et al. (2010). PMID: 21186916 LBC1936

 

Caffeine consumption and cognitive function at age 70: the Lothian Birth Cohort 1936 study. Psychosomatic Medicine.

Corley, J., et al. (2010). PMID: 19995882 LBC1936

 

Are processing speed tasks biomarkers of cognitive ageing? Psychology and Aging.

Deary, I. J., et al. (2010). PMID: 20230141 LBC1936

 

Complement factor H antibodies and age-related macular degeneration. Investigative Ophthalmology and Visual Science.

Dhillon, B., et al. (2010).  PMID: 20592223 LBC1921

 

A revised ADL/IADL instrument increases interpretive power: theoretical application for functional tasks exercise. Gerontology.

Fieo, R., et al. (2010). PMID: 20051661 LBC1921

 

The structure of the Hospital Anxiety and Depression Scale in four cohorts of community-based, healthy older people: the HALCyon Programme. International Psychogeriatrics.

Gale, C. R., et al. (2010). PMID: 20214846 LBC1921

 

Human intelligence and ploymorphism in the DNA methyltransferase genes involves in epigenetic marking. PLoS One.

Haggarty, P., et al. (2010). PMID: 20593030 LBC1936

 

Variation in DISC1 is associated with anxiety, depression and emotional stability in elderly women. Molecular Psychiatry.

Harris, S. E., et al. (2010). doi:10.1038/mp.2009.88 LBC1921 & LBC1936

 

Common variants of large effect in F12, KNG1 and HRG are associated with activated partial thromboplastin time. American Journal of Human Genetics.

Houlihan, L. M., et al. (2010). PMID: 20303064 LBC1921 & LBC1936

 

Replication association analysis of S100B and cognitive ageing. Psychiatric Genetics. Houlihan, L. M., et al. (2010). PMID: 20473040 LBC1936

 

Variation in the uric acid transporter gene (SLC2A9) and memory performance. Human Molecular Genetics.

Houlihan, L. M., et al. (2010). PMID: 20197412 LBC1921 & LBC1936

 

Intergenerational class mobility in Britain: a comparative look across three generations in the Lothian Birth Cohort 1936. Intelligence.

Johnson, W., et al. (2010). doi:10.1016/j.intell.2009.11.010 LBC1936

 

The pivotal role of education in the association between ability and social class attainment: a look across three generations. Intelligence.

Johnson, W., et al. (2010). doi:10.1016/j.intell.2009.11.008 LBC1921

 

Location in cognitive and residential space at age 70 reflects a lifelong trait over parental and environmental circumstances: the Lothian Birth Cohort 1936. Intelligence.

Johnson, W., et al. (2010). doi:10.1016/j.intell.2010.04.001 LBC1936

 

Association of existing and new candidate genes for anxiety, depression and personality traits in old people. Behavior Genetics.

Luciano, M., et al. (2010). PMID: 20052609 LBC1921

 

Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples. Behavior Genetics.

Marioni, R. E., et al. (2010). PMID: 19821022 LBC1936

 

Differences in haematological profile of healthy 70 year old men and women: normal ranges with confirmatory factor analysis. BMC Blood Disorders.

McIlhagger, R., et al. (2010). PMID: 20540715 LBC1936

 

Failure to validate association between variants on 12p13 and ischaemic stroke. New England Journal of Medicine.

Nalls, M. A., et al. (2010). doi:10.1056/NEJMc0910050  LBC1936

 

White matter integrity in the splenium of the corpus callosum is related to successful cognitive ageing and partly mediates the protective effect of an ancestral polymorphism in ADRB2. Behavior Genetics.

Penke, L., et al. (2010).. PMID: 20087642 LBC1936

 

A general factor of brain white matter integrity predicts information processing speed in healthy older people. Journal of Neuroscience.

Penke, L., et al. (2010). PMID: 20519531 LBC1936

 

Carotid intima media thickness and cerebrovascular disease in community-dwelling older people without stroke. Stroke.

Shenkin, S. D., et al. (2010). PMID: 20651261 LBC1936

 

Renal function in a narrow-age cohort of adults at age 79 and 87 years. Age and Ageing. Starr, J. M., & Deary, I. J. (2010). PMID: 20823126 LBC1921

 

Height and intelligence in the Lothian Birth Cohort 1921: a longitudinal study. Age and Ageing. Starr, J. M., et al. (2010). PMID: 20065355 LBC1921

 

Confirmed rare copy number variants implicate novel genes in schizophrenia. Biochemical Society Transactions.

Tam, G. W. C., vet al. (2010). PMID: 20298200 LBC1936

 

2009

 

Diffusion tensor and magnetization transfer MRI measurements of periventricular white matter intensities in old age. Neurobiology of Aging.

Bastin, M. E., et al. (2009). PMID: 17624630 LBC1921

 

Association of KIBRA and memory. Neuroscience Letters.

Bates, T. C., et al. (2009). PMID: 19397951  LBC1921

 

A functional polymorphism under positive evolutionary selection in ADRB2 is associated with human intelligence with opposite effects in the young and the elderly. Behavior Genetics. Bochdanovits, Z., et al. (2009). PMID: 18855131 LBC1936

 

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder. Molecular Psychiatry.

Hennah, W., et al. (2009). PMID: 18317464 LBC1921

 

Replication study of candidate genes for cognitive abilities: the Lothian Birth Cohort 1936. Genes, Brain and Behavior.

Houlihan, L. M., et al. (2009). PMID: 19077115 LBC1936

 

A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder and depression. American Journal of Human Genetics.

Knight, H. M., et al. (2009). PMID: 19944402 LBC1936

 

Variants in doublecortin- and calmodulin kinase like 1 (DCLK1), a gene up-regulated by BDNF, are associated with memory and general cognitive abilities. PLoS One.

Le Hellard, S., et al. (2009). PMID: 19844571 LBC1921 and LBC1936

 

Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study. Psychology and Aging.

Luciano, M., et al. (2009). PMID: 19290744 LBC1936

 

Apolipoprotein E is not related to memory abilities at 70 years of age. Behavior Genetics. Luciano, M., et al. (2009). PMID: 18946731 LBC1936

 

Reverse causation in the association between C reactive protein and fibrinogen levels and cognitive abilities in an aging sample. Psychosomatic Medicine.

Luciano, M., et al. (2009). PMID: 19398500 LBC1936

 

Variation in the dysbindin gene and normal cognitive function in three independent population samples. Genes, Brain and Behavior.

Luciano, M., et al. (2009). PMID: 19077176 LBC1936

 

Symmetric faces are a sign of successful cognitive aging. Evolution and Human Behavior. Penke, L., et al. (2009). doi:10.1016/j.evolhumbehav.2009.06.001 LBC1921

 

Birth parameters are associated with later life white matter integrity in community-dwelling older people. Stroke.

Shenkin, S. D., et al. (2009). PMID: 19213950 LBC1921

 

Birth parameters and cognitive ability in older age: a follow-up study of people born in 1921-1926. Gerontology.

Shenkin, S. D., et al. (2009). PMID: 18843177 LBC1921

 

Maximum (prior) brain size, not atrophy, correlates with cognition in community-dwelling old people: a cross-sectional neuroimaging study. BMC Geriatrics.

Shenkin, S. D., et al. (2009). PMID: 19341481 LBC1921

 

2008

 

Mental ability in childhood and cognitive aging. Gerontology.

Gow, A. J., et al. (2008). PMID: 18287787 LBC1921

 

PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. Neuroscience letters.

Johnson, W., et al. (2008). PMID: 18280041  LBC1921

 

Testing replication of a 5-SNP set for general cognitive ability in six population samples. European Journal of Human Genetics.

Luciano, M., et al. (2008). PMID: 18493267 LBC1921

 

Childhood cognitive ability and risk of late-onset Alzheimer and vascular dementia. Neurology. McGurn, B., et al. (2008). PMID: 18579804 LBC1921

 

Is there information contained within the sentence-writing component of the Mini Mental State Examination? A retrospective study of community dwelling older people. International Journal of Geriatric Psychiatry.

Shenkin, S. D., et al. (2008). PMID: 18563868 LBC1921

 

Predictors of tooth loss in the 1921 Lothian Birth Cohort. Age and Ageing.

Starr, J. M., et al. (2008). PMID: 18033778  LBC1921

 

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 from the 1932 Scottish Mental Survey. Mechanisms of Aging and Development.

Starr, J. M., et al. (2008). PMID: 18977241 LBC1921

 

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet.

Tenesa, A., et al. (2008).  PMID: 18372901 LBC1936

 

2007

 

The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond. BMC Geriatrics.

Deary, I. J., et al. (2007). PMID: 18053258 LBC1936

 

Social support and successful ageing: investigating the relationships with lifetime cognitive change and life satisfaction. Journal of Individual Differences.

Gow, A. J., et al. (2007). doi:10.1027/1614-0001.28.3.103 LBC1921

 

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. BMC Genetics.

Harris, S. E., et al. (2007). PMID: 17601350 LBC1921

 

No association of CETP genotype with cognitive function or age-related cognitive change. Neuroscience Letters.

Johnson, W., et al. (2007) PMID: 17531380 LBC1921

 

The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. Human Molecular Genetics.

Mekel-Bobrov, N., et al. (2007). PMID: 17220170 LBC1921

 

Renal function and cognition in the 1932 Scottish Mental Survey Lothian cohort. Age & Ageing.

Munang, L., et al. (2007). PMID: 17255090 LBC1921

 

The association between retinal vascular network geometry and cognitive ability in an elderly population. Investigative Ophthalmology & Visual Science.

Patton, N., et al. (2007). PMID: 17460252 LBC1921

 

Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation. Journal of Medical Genetics.

Sisodiya, S. M., et al. (2007). PMID: 17237123 LBC1921

 

Association between telomere length and heart disease in a narrow age cohort of older people. Experimental Gerontology.

Starr, J. M., et al. (2007). PMID: 17267157 LBC1921

 

Complement C3 variant increases risk of age-related macular degeneration. New England Journal of Medicine.

Yates, J. R. W., et al. (2007). PMID: 17634448 LBC1921

 

2006

 

White matter integrity and cognition in childhood and old age. Neurology.

Deary, I. J., et al. (2006). PMID: 16505302 LBC1921

 

Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change. Neuroscience Letters.

Deary, I. J., et al. (2006).  PMID: 16236446 LBC1921

 

Physical fitness and lifetime cognitive change. Neurology.

Deary, I. J., et al. (2006). PMID: 17030752 LBC1921

 

The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people. Neuroscience Letters.

Harris, S. E., et al. (2006). PMID: 16919874 LBC1921

 

The brain derived neurotrophic factor polymorphism is associated with age-related change in reasoning skills. Molecular Psychiatry.

Harris, S. E., et al. (2006). PMID: 16446742 LBC1921

 

2005

 

Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing. Neuroscience Letters, 373, 110-114.

Deary, I. J., et al. (2005). PMID: 15567563 LBC1921

 

KLOTHO genotype and cognitive ability in childhood and old age in the same individuals. Neuroscience Letters, 378, 22-27.

Deary, I. J., et al. (2005). PMID: 15763166 LBC1921

 

Goldberg’s ‘IPIP’ Big-Five markers: internal consistency and concurrent validation in Scotland. Personality and Individual Differences, 39, 317-329.

Gow, A. J., et al. (2005). doi:10.1016/j.paid.2005.01.011 LBC1921

 

The personality-intelligence interface: insights from an ageing cohort. Personality and Individual Differences, 39, 751-761.

Gow, A. J., et al. (2005). doi:10.1016/j.paid.2005.01.028  LBC1921

 

Lifetime intellectual function and satisfaction with life in old age: longitudinal cohort study. BMJ, 331(7509), 141 -142.

Gow, A. J., et al. (2005). doi:10.1136/bmj.38531.675660.F7 LBC1921

 

The functional COMT polymorphism, Val158Met, is associated with Logical Memory and the personality trait intelligence/imagination in a cohort of healthy 79 year olds. Neuroscience Letters, 385, 1-6.

Harris, S. E., et al. (2005). PMID: 15979789 LBC1921

 

Genetic influences on oxidative stress and their association with normal cognitive ageing. Neuroscience Letters, 386, 116-120.

Kachiwala, S. J., et al. (2005). PMID: 16023289 LBC1921

 

Cognitive correlates of cerebral white matter lesions and water diffusion tensor parameters in community dwelling older people. Cerebrovascular Diseases, 20, 310-318.

Shenkin, S. D., et al. (2005). PMID: 16141715  LBC1921

 

Vitamin B12, serum folate, and cognitive change from age 11 to age 79. Journal of Neurology, Neurosurgery and Psychiatry, 76, 291-292.

Starr, J. M., et al. (2005). PMID: 15654057 LBC1921

 

Association between genotype at an exonic SNP in DISC1 and normal cognitive ageing. Neuroscience Letters, 389, 41-45.

Thomson, P. A., et al. (2005). PMID: 16054297 LBC1921

 

2004

Apolipoprotein E gene variability and cognitive functions at age 79: follow up of the Scottish Mental Survey 1932. Psychology and Aging.

Deary, I. J., et al. (2004). PMID: 15222832 LBC1921

 

The impact of childhood intelligence on later life: following up the Scottish Mental Surveys of 1932 and 1947. Journal of Personality and Social Psychology.

Deary, I. J., et al. (2004). PMID: 14717632 LBC1921

 

Pronunciation of irregular words is preserved in dementia, validating premorbid IQ estimation. Neurology.

McGurn, B., et al. (2004). PMID: 15079021 LBC1921

 

11Beta-Hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics. Proceedings of the National Academy of Sciences of the United States of America.

Sandeep, T. C., et al. (2004). PMID: 15071189 LBC1921

 

Life long changes in cognitive ability are associated with prescribed medications in old age. International Journal of Geriatric Psychiatry, 19, 327-332.

Starr, J. M., et al. (2004). PMID: 15065225 LBC1921

 

2003

Smoking and cognitive change from age 11 to age 80. Journal of Neurology, Neurosurgery and Psychiatry.

Deary, I. J., et al. (2003). PMID: 12810811 LBC1921

 

Childhood and current cognitive function in healthy 80-year-olds: A DT-MRI study. NeuroReport.

Shenkin, S. D., et al.(2003). PMID: 12634481 LBC1921

 

Lack of association between polymorphisms in ACE and MTHFR genes and normal cognitive ageing. Neuroscience Letters.

Visscher, P. M., et al. (2003). PMID: 12875914 LBC1921

 

2002

Cognitive change and the APOE e4 allele. Nature.

Deary, I. J.,et al. (2002). PMID: 12198535 LBC1921

 

2001

Birth weight and cognitive function at age 11 years: The Scottish Mental Survey 1932. Archives of Disease in Childhood.

Shenkin, S. D., et al (2001). PMID: 11517097 LBC1921